Periodontal Inflamed Surface Area Mediates the Link between Homocysteine and Blood Pressure

Here, we assess the association between homocysteine (Hcy) serum levels and periodontal status in a large representative sample of National Health Nutrition Examination Survey (NHANES). Using 2001–2002 2003–2004 NHANES databases, participants with examination, medical self-reported data, blood pressure (BP) samples to determine complete count, C-reactive protein (CRP) Hcy levels. We then calculated inflamed surface area (PISA) epithelial (PESA). Multivariable regression analysis explored Hcy, measures BP. Mediation was performed understand effect PISA PESA link 4021 fulfilled inclusion criteria. showed significant correlations systolic BP, diastolic PISA, age. be significantly associated both for crude adjusted models (p < 0.01), but not > 0.05). In mediated 17.4% 0.9%. 16.3% 47.2%. conclusion, periodontitis are associated. Further, BP Future studies shall deepen mechanisms by which increase clinical situation periodontitis.